Holly Van Remmen, Ph.D.
Education
Postdoctoral Fellow 1995, University of Texas Health Science Center, Texas
PhD 1991, University of Texas Health Science Center, Texas
BS 1983, Eastern Illinois University, Illinois
Research Overview
There are two interconnected lines of research in the Van Remmen laboratory. The first is the study of how oxidative stress and mitochondrial function modulate age-related loss of skeletal muscle mass and function (sarcopenia), neuromuscular degeneration (Amyotrophic Lateral Sclerosis (ALS)) and changes in motor neurons in aging and neuromuscular disease. Our research uses mouse models of altered oxidative stress and mitochondrial function to probe these pathways. We utilize a number of experimental approaches from in vivo assessment of animal behavior, motor function, neuronal and muscle function to approaches in cell culture, tissue samples or in isolated mitochondria. At the biochemical level, we interrogate pathways involved in aging and disease using molecular approaches to measure changes in mRNA and proteins. Finally, the Van Remmen laboratory is also a Core facility in the Nathan Shock Center for Excellence in the Biology of Aging.
Van Remmen Lab
Holly Van Remmen, Ph.D.
Principal Investigator
Bumsoo Ahn, Ph.D.
Research Assistant Member
Shylesh Bhaskaran, Ph.D.
Staff Scientist
Kavithalakshmi Sataranatarajan, Ph.D
Staff Scientist
Jacob Brown, Ph.D.
Post Doctoral Fellow
Yang Xu, Ph.D.
Post Doctoral Fellow
Gavin Pharaoh, Ph.D.
Post Doctoral Fellow
Rojina Ranjit
Research Assistant
Ashley Murphy
Senior Laboratory Technician
Ryan McIntire
Research Technician
Lauren Oliver
Research Technician
Parker Kneis
Affiliate, Research Technician
Kat Piekarz
Graduate Student
Contact
Oklahoma Medical Research Foundation
825 NE 13th Street, Chapman Building S108-S112
Oklahoma City OK 73104
Lab Phone: (405) 271-2653
Office Phone: (405) 271-2520
