Wan Hee Yoon, Ph.D.
Education
Postdoctoral Drosophila and Human Genetics 2016, Howard Hughes Medical Institute, Baylor College of Medicine
PhD Drosophila Genetics 2011, Johns Hopkins University School of Medicine
MS Biology 1999, Yonsei University, Seoul, South Korea
BS Biology 1997, Yonsei University, Seoul, South Korea
Research Review
Metabolism is a series of biochemical reactions essential for all living life. Mitochondria are compartments in the cells, and play a crucial role in metabolism. Dysfunction of mitochondria and miscommunication between mitochondria and other cellular compartments causes abnormal metabolism, which underlies numerous human diseases.
My work is focused on the study of the function of mitochondrial genes in fruit flies and patient-derived iPS cells: these include genes whose loss of functions causes neurodevelopmental diseases and a Charcot-Marie-Tooth Neuropathy Type 2A (CMT2A)-like neurological syndrome and neurodegenerative and metabolic diseases accompanied by alpha-ketoglutarate dehydrogenase deficiency. Unraveling the cellular and molecular mechanisms underlying disease processes in the fly and human cells will ultimately help us better understand the pathogenesis of the neurological diseases.
Yoon Lab
Wan Hee Yoon, Ph.D.
Principal Investigator
Patricia Goncalves Barbalho, Ph.D.
Post-Doctoral Fellow
Jae Sun Kang
Research Technician
Lorraine Yap
Senior Research Technician
Yo Han Park
Research Technician
Karen Vargas Parra
Lab Technician
Contact
Oklahoma Medical Research Foundation
Aging & Metabolism Research Program, W303
825 N.E. 13th Street
Oklahoma City OK 73104
Phone: (405) 271-1574